chr	type	count	pos	neg
chr1	Cohort	2214	0.017163505	-0.014905149
chr1	LOF	2214	0	0
chr1	LOF	2214	0	0
chr1	LOF	2214	0	0
chr1	LOF	2214	0	0
chr1	Missense 2	2214	0.001355014	-0.000903342
chr1	Missense 3	2214	0.005420054	-0.003161698
chr1	Splice	2214	0.004516712	-0.005871725
chr10	Cohort	1287	0.017094017	-0.009324009
chr10	LOF	1287	0	0
chr10	LOF	1287	0	0
chr10	LOF	1287	0	0
chr10	LOF	1287	0	0
chr10	Missense 2	1287	0.00E+00	0
chr10	Missense 2	1287	0	-0.003885004
chr10	Missense 3	1287	0.004662005	-0.005439005
chr10	Splice	1287	0.003885004	-0.005439005
chr11	Cohort	1284	0.007009346	-0.024143302
chr11	LOF	1284	0	0
chr11	LOF	1284	0	0
chr11	LOF	1284	0	0
chr11	LOF	1284	0	0
chr11	Missense 2	1284	0	0
chr11	Missense 2	1284	0	-0.003894081
chr11	Missense 3	1284	0.001557632	-0.007009346
chr11	Splice	1284	0	-0.008566978
chr11	Splice	1284	0	0
chr12	Cohort	1266	0.007109005	-0.015797788
chr12	LOF	1266	0.00E+00	0
chr12	LOF	1266	0	0
chr12	LOF	1266	0	0
chr12	LOF	1266	0	0
chr12	Missense 2	1266	0.000789889	-0.002369668
chr12	Missense 3	1266	0.003949447	-0.006319115
chr12	Splice	1266	0.003159558	-0.007898894
chr13	Cohort	945	0.014814815	-0.016931217
chr13	LOF	945	0	0
chr13	LOF	945	0	0
chr13	LOF	945	0	0
chr13	LOF	945	0	0
chr13	Missense 2	945	0	-0.001058201
chr13	Missense 2	945	0	0
chr13	Missense 3	945	0.004232804	-0.003174603
chr13	Splice	945	0.001058201	-0.002116402
chr14	Cohort	868	0.019585253	-0.006912442
chr14	LOF	868	0	0
chr14	LOF	868	0	0
chr14	LOF	868	0	0
chr14	LOF	868	0	0
chr14	Missense 2	868	0	0
chr14	Missense 2	868	0	0
chr14	Missense 2	868	0	0
chr14	Missense 2	868	0	0
chr14	Missense 3	868	0.004608295	-0.002304147
chr14	Splice	868	0.005760369	-0.001152074
chr15	Cohort	744	0.02016129	-0.002688172
chr15	LOF	744	0	0
chr15	LOF	744	0	0
chr15	LOF	744	0	0
chr15	LOF	744	0	0
chr15	Missense 2	744	0	0
chr15	Missense 2	744	0	0
chr15	Missense 2	744	0	0
chr15	Missense 2	744	0	0
chr15	Missense 3	744	0.002688172	0
chr15	Missense 3	744	0	0
chr15	Splice	744	0.00672043	0
chr15	Splice	744	0	0
chr16	Cohort	747	0.030789826	-0.010709505
chr16	LOF	747	0	0
chr16	LOF	747	0	0
chr16	LOF	747	0	0
chr16	LOF	747	0	0
chr16	Missense 2	747	0	0
chr16	Missense 2	747	0	-0.004016064
chr16	Missense 3	747	0.005354752	-0.010709505
chr16	Splice	747	0.008032129	-0.009370817
chr17	Cohort	762	0.028871391	-0.009186352
chr17	LOF	762	0	0
chr17	LOF	762	0.00E+00	0
chr17	LOF	762	0	0
chr17	LOF	762	0	0
chr17	Missense 2	762	0.001312336	0
chr17	Missense 2	762	0	0
chr17	Missense 3	762	0.005249344	-0.001312336
chr17	Splice	762	0.010498688	-0.002624672
chr18	Cohort	730	0.009589041	-0.010958904
chr18	LOF	730	0	0
chr18	LOF	730	0	0
chr18	LOF	730	0	0
chr18	LOF	730	0	0
chr18	Missense 2	730	0	0
chr18	Missense 2	730	0	-0.001369863
chr18	Missense 3	730	0.005479452	-0.004109589
chr18	Splice	730	0	0
chr18	Splice	730	0	-0.002739726
chr19	Cohort	537	0.03538175	-0.001862197
chr19	LOF	537	0	0
chr19	LOF	537	0	0
chr19	LOF	537	0	0
chr19	LOF	537	0	0
chr19	Missense 2	537	0	0
chr19	Missense 2	537	0	0
chr19	Missense 2	537	0	0
chr19	Missense 2	537	0	0
chr19	Missense 3	537	0.003724395	-0.001862197
chr19	Splice	537	0	0
chr19	Splice	537	0.011173184	0
chr2	Cohort	2336	0.017123288	-0.014554795
chr2	LOF	2336	0	0
chr2	LOF	2336	0	0
chr2	LOF	2336	0	0
chr2	LOF	2336	0	0
chr2	Missense 2	2336	0.000856164	-0.000856164
chr2	Missense 3	2336	0.003424658	-0.001284247
chr2	Splice	2336	0.000856164	-0.001712329
chr20	Cohort	590	0.015254237	0
chr20	Cohort	590	0	0
chr20	LOF	590	0	0
chr20	LOF	590	0	0
chr20	LOF	590	0	0
chr20	LOF	590	0	0
chr20	Missense 2	590	0	0
chr20	Missense 2	590	0	0
chr20	Missense 2	590	0	0
chr20	Missense 2	590	0	0
chr20	Missense 3	590	0	0
chr20	Missense 3	590	0	-0.003389831
chr20	Splice	590	0	0
chr20	Splice	590	0	0
chr20	Splice	590	0	0
chr20	Splice	590	0	0
chr21	Cohort	327	0.03058104	-0.003058104
chr21	LOF	327	0	0
chr21	LOF	327	0	0
chr21	LOF	327	0	0
chr21	LOF	327	0	0
chr21	Missense 2	327	0	0
chr21	Missense 2	327	0	0
chr21	Missense 2	327	0	0
chr21	Missense 2	327	0	0
chr21	Missense 3	327	0.009174312	0
chr21	Missense 3	327	0	0
chr21	Splice	327	0	0
chr21	Splice	327	0.003058104	0
chr22	Cohort	321	0.028037383	-0.003115265
chr22	LOF	321	0	0
chr22	LOF	321	0	0
chr22	LOF	321	0	0
chr22	LOF	321	0	0
chr22	Missense 2	321	0	0
chr22	Missense 2	321	0	0
chr22	Missense 2	321	0	0
chr22	Missense 2	321	0	0
chr22	Missense 3	321	0.003115265	-0.003115265
chr22	Splice	321	0	0
chr22	Splice	321	0	-0.00623053
chr3	Cohort	1902	0.006309148	-0.015247108
chr3	LOF	1902	0	0
chr3	LOF	1902	0	0
chr3	LOF	1902	0	0
chr3	LOF	1902	0	0
chr3	Missense 2	1902	0	-0.001051525
chr3	Missense 2	1902	0	0
chr3	Missense 3	1902	0.002628812	-0.005257624
chr3	Splice	1902	0.001577287	-0.005257624
chr4	Cohort	1850	0.01027027	-0.026486486
chr4	LOF	1850	0	0
chr4	LOF	1850	0	0
chr4	LOF	1850	0	0
chr4	LOF	1850	0	0
chr4	Missense 2	1850	0.000540541	-0.000540541
chr4	Missense 3	1850	0.001621622	-0.008108108
chr4	Splice	1850	0.002162162	-0.003783784
chr5	Cohort	1734	0.009803922	-0.013264129
chr5	LOF	1734	0	0
chr5	LOF	1734	0	0
chr5	LOF	1734	0	0
chr5	LOF	1734	0	0
chr5	Missense 2	1734	0	0
chr5	Missense 2	1734	0	-0.002306805
chr5	Missense 3	1734	0.001730104	-0.00461361
chr5	Splice	1734	0.001153403	-0.004036909
chr6	Cohort	1655	0.013897281	-0.018126888
chr6	LOF	1655	0	0
chr6	LOF	1655	0	0
chr6	LOF	1655	0	0
chr6	LOF	1655	0	0
chr6	Missense 2	1655	0	0
chr6	Missense 2	1655	0	0
chr6	Missense 2	1655	0.00E+00	0
chr6	Missense 2	1655	0	0
chr6	Missense 3	1655	0.003021148	-0.00060423
chr6	Splice	1655	0.001812689	-0.001208459
chr7	Cohort	1524	0.018372703	-0.019028871
chr7	LOF	1524	0	0
chr7	LOF	1524	0	0
chr7	LOF	1524	0	0
chr7	LOF	1524	0	0
chr7	Missense 2	1524	0	0
chr7	Missense 2	1524	0	-0.005905512
chr7	Missense 3	1524	0.00328084	-0.00984252
chr7	Splice	1524	0.004593176	-0.007217848
chr8	Cohort	1337	0.010471204	-0.007479432
chr8	LOF	1337	0	0
chr8	LOF	1337	0	0
chr8	LOF	1337	0	0
chr8	LOF	1337	0	0
chr8	Missense 2	1337	0	0
chr8	Missense 2	1337	0	0
chr8	Missense 2	1337	0	0
chr8	Missense 2	1337	0	0
chr8	Missense 3	1337	0.003739716	-0.002991773
chr8	Splice	1337	0.002243829	-0.002991773
chr9	Cohort	1123	0.020480855	-0.012466607
chr9	LOF	1123	0	0
chr9	LOF	1123	0	0
chr9	LOF	1123	0	0
chr9	LOF	1123	0	0
chr9	Missense 2	1123	0	-0.003561888
chr9	Missense 2	1123	0	0
chr9	Missense 3	1123	0.003561888	-0.00890472
chr9	Splice	1123	0.005342832	-0.008014248